Biomarkers in Lupus
The study of lupus biomarkers to diagnose, monitor, and predict disease activity has become a priority. So what exactly is a biomarker?
According to NCBI, “based on scientific and clinical rationale, a biomarker is defined as a measurement, including but not limited to a genetic, biological, biochemical, molecular, or imaging event whose alterations correlate with the pathogenesis and/or manifestations of a disease and can be evaluated qualitatively and/or quantitatively in laboratories.”
Due to the complexity of systemic lupus erythematosus, biomarkers have become crucial to presenting disease mechanisms, evaluating patients, and dictating treatment options. Additionally, biomarkers can prove to be reliable indicators for patients that are at higher-risk of developing lupus, long before diagnosis.